专利名称:3- Substituted-2-(methylamino) phenyl!-4- 2-oxo-2-(hetero-cyclic) ethyl!- 5-substituted-1,2,4-triazoles
发明人:Peter C. Wade,Berthold Richard Vogt申请号:US05/680315申请日:19760426公开号:US04020064A公开日:19770426
摘要:Compounds of the following formula and their pharmaceutically acceptablesalts ##STR1## wherein R.sub.1 and R.sub.4 are the same or different and are each a fiveor six membered N containing heterocycle attached at an available N atom; R.sub.2 ishydrogen, alkyl, trifluoromethyl, phenyl, benzyl, --(CH.sub.2).sub.n --R.sub.4 or --(CH.sub.2).sub.n --N(alkyl).sub.2 ; R.sub.3 is hydrogen, halogen, nitro, trifluoromethyl, alkyl,alkoxy, or alkylthio; and n is an integer from 1 to 4; are disclosed. These compounds areuseful as anti-inflammatory agents.
申请人:E. R. SQUIBB & SONS, INC.
代理人:Lawrence S. Levinson,Merle J. Smith,Stephen B. Davis
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